Editorial for “Regulatory RNAs in the nervous system”

P87: The Role of the Long Non-Coding RNA Sequences (LncRNAs) in Neurological Disorders

Precise interpretation of the transcriptome sequences in the several species showed that the major part of genome has been transcribed; however, just a few amounts of the transcription sequences have open-reading frames which are conversed during the evolution. So, it is unlikely that many of the transcribed sequences code the proteins. Among the all human non-coding transcripts, at least 10000...

Editorial: Non-Coding RNAs in Neurodevelopmental Disorders

Small RNA-mediated gene regulation in neurodevelopmental disorders.

An expanding assortment of small, noncoding RNAs identified in the nervous system suggests a strong connection between their combinatorial regulatory potential and the complexity of the nervous system. Misregulation of these small regulatory RNAs could contribute to the abnormalities in brain development that are associated with neurodevelopmental disorders. Here we give an overview of the dive...

Small RNAs inNeurological Disorders

Small RNAs (ribonucleic acids) are a group of noncoding RNA molecules with modulation functions that span a broad range, from RNA modification to protein synthesis regulation. The expression of small RNAs is found to be widespread in all eukaryotes, and more than a third of protein-codinggenes in thehumangenomeare regulated by small RNAs. Mounting evidence suggests that the appropriate spatiote...

Editorial on the Special Issue: Regulation by Non-Coding RNAs

This Special Issue of IJMS is devoted to regulation by non-coding RNAs and contains both original research and review articles. An attempt is made to provide an up-to-date analysis of this very fast moving field and cover regulatory roles of both microRNAs and long non-coding RNAs. Multifaceted functions of these RNAs in normal cellular processes, as well as in disease progression, are highligh...